Buprenorphine is a semi-synthetic opiate with partial agonist and antagonist actions. It is a powerful analgesic, 25 to 40 times more potent than morphine. It is used for the treatment of moderate to severe pain, peri-operative analgesia and opioid dependence. Overdose symptoms of the drug include confusion, dizziness, pinpoint pupils, hallucinations, hypotension, respiratory difficulty, seizures, and coma.
Administration: Injection, infusion, transdermal patch, or sublingual tablet.
Elimination: Buprenorphine is metabolized by N-dealkylation to norbuprenorphine, followed by glucuronide conjugation of both buprenorphine (BUP) and norbuprenorphine (nor-BUP) for excretion in urine. The amount of norbuprenorphine metabolite excreted in urine generally exceeds that of conjugated buprenorphine.
Abuse Potential: Buprenorphine is subject to abuse and diversion. It is often used recreationally by insufflation, and commonly used by illicit users to prevent withdrawals in between doses of their opiate of choice.
Storage Temp: 2-8°C
| Quantity | Each |
|---|---|
| Hazardous | No |
| Is Featured | No |
