Protriptyline is a second-generation tricyclic antidepressant (TCA) marketed under the trade name Vivactil, for treatment of major depression and ADHD. This certified Snap-N-Spike solution is applicable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, or urine drug testing. Protriptyline is unique among TCAs, since it has energizing, rather than sedating effects.