A certified multi-component solution mix of synthetic cannabinoids JWH-019, JWH-122, JWH-081, and AM-2201. Cases of abuse for these four synthetic cannabinoids, similar in structure to JWH-018 and JWH-073, have been observed across the US from California and Texas to Pennsylvania and Missouri. This certified solution mix is suitable for GC/MS and LC/MS applications in forensic analysis, clinical toxicology, and urine drug testing.